Glucose is an important energy source for many cells, including brain and red blood cells. It is also used by some liver cells and adipose tissue for storing energy.
Glucose is produced during phosynthesis in plants and it is produced in humans by hepatic gluconeogenesis. It is degraded in the body in a series of cellular reactions, beginning with glycolysis.
Energy
Glucose is the main source of energy for most living organisms. It is a precursor to several important compounds including starch, cellulose, and glycogen (as well as oligosaccharides).
Several enzymes use phosphorylated glucose to add a sugar group to other molecules in an organic chemical process called glycosylation. This can be very important for the functioning of proteins and lipids.
Glucose is found in two naturally occurring forms, L-glucose and D-glucose. Both contain identical glucose molecules but arranged in mirror reflections. The D-glucose form polarises light clockwise and the L-glucose form polarises it anticlockwise.
Carbohydrates
Glucose is the main source of energy for living organisms. It is also the basis for many cellular processes. Among the most important are the production of glucose polymers (polysaccharides) such as starch, cellulose and glycogen; lipids; and oligosaccharides consisting of glucose and other sugars.
Moreover, glucose is added onto proteins and lipids in a process called glycosylation to give them structure. It is also used as a substrate in the process of fermentation to produce ethanol, an alcohol.
Carbohydrates are found in a wide range of foods, and they come in different forms and types. Eating carbohydrates from healthy sources such as whole grains, vegetables, fruits and beans is a key to a good diet.
Carbohydrates provide fuel for the central nervous system and energy for working muscles throughout the day. However, they can be harmful when consumed in excess. A high-glycemic diet can increase your risk of heart disease, diabetes and obesity.
Glycogen
Glycogen is the body's main energy storage mechanism. It is stored in mainly the liver and muscles and is distributed to other tissues as free glucose.
Glycogen has a polymer structure with long linear chains of glucose residues linked by a-1,4 glycosidic bonds. These glucose units form a helical polymer with approximately every ten residues forming a branch with another chain of glucose residues.
These branches are bonded together with an alpha-acetal linkage, -C(OH)H-O-, which occurs when 2 alkoxy groups bond to the same carbon atom (C-1 and C-4 or C-5). In solutions, open-chain forms of glucose exist in equilibrium with several cyclic isomers, each containing a ring of hydroxyls closed by one oxygen atom.
Muscle glycogen accounts for approximately 1-2% of muscle weight, and is primarily located in intermyofibrillar regions. When muscle glycogen is depleted, a transport protein called hexokinase will break it down and release glucose into the bloodstream.
Polysaccharides
Polysaccharides are complex, branched carbohydrates that are formed when monosaccharides or disaccharides link together by glycosidic bonds. These bonds are formed by an oxygen atom between two carbon rings.
Polysaccharide chains have unique properties that differ from one another, including their composition, bonding, degree of branching and molecular weights. These structural characteristics are important in understanding their physicochemical and biological activities.
Almost all polysaccharides are linked by glycosidic bonds. These bonds form during a dehydration reaction, when a water molecule is removed from the sugar residue and a hydroxyl group is lost from a carbon.
Polysaccharides are used as structural components of cell walls and extracellular structures in plants, insects, and fungi. Some of them also act as energy storage. Examples of these include cellulose and chitin. They are also found in hyaluronic acid, a substance that is important for joint fluid and connective tissue.